Prof. Pericàs Group is pioneer in developing highly active and enantioselective organocatalysts immobilized onto polymers and other materials, and suitable for the continuous production of enantiopure compounds or a library of them using the same batch of catalyst and only changing the starting materials as you can see below.
The supported catalysis combines the advantages of homogeneous and heterogeneous processes:
- the catalytic process takes place in an homogeneous environment, providing the same opportunities for selectivity control than homogeneous catalysis,
- the catalyst is readily separable from reaction products, being recycled and can be reused for a more sustainable process and,
- they are suitable for continuous operation, with suppression of wasteful work-up
Over the last years, the Pericàs laboratory at ICIQ has been engaged in a broad research program aimed at developing a complete toolkit of polymer-supported and magnetic nanoparticle-immobilized catalysts with optimized characteristics of catalytic activity, high induced stereoselectivity and extended life cycle.
The ultimate goal of this research has been the development of single-pass, catalytic and enantioselective flow versions of the most relevant processes for organic synthesis, contributing in this manner to a more sustainable practice of chemical synthesis. Our laboratory at ICIQ has been pioneer in this effort, being recognized as one of the leaders in the field.
If you want to know more about our research group, please click on the next video:
You can also visit the Pericàs Research Group – official website